Concepedia

Publication | Open Access

TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients

DOIFull Paper Access

183

Citations

40

References

2015

Year

Dewan Md Sakib Hossain, Sumanta K. Pal, Dayson Moreira, Priyanka Duttagupta, Qifang Zhang, Haejung Won, Jeremy Jones, Massimo D’Apuzzo, Stephen J. Forman, Marcin Kortylewski
Clinical Cancer Research

Abstract

Overall, we demonstrate the accumulation of granulocytic MDSCs with prostate cancer progression and the feasibility of using TLR9-targeted STAT3siRNA delivery strategy to alleviate MDSC-mediated immunosuppression.

References

YearCitations

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