A modular approach for integrative analysis of large-scale gene-expression and drug-response data

Gene Ontology: tool for the unification of biology

Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +9

<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma

Monika E. Hegi, Annie‐Claire Diserens, Thierry Gorlia et al. · New England Journal of Medicine · 2005 · 7.3K citations · Full text

Medicine, Molecular Biology, Oncology +17

Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine

M H Zweig, Gregory Campbell · Clinical Chemistry · 1993 · 6.6K citations

Public Health, Biostatistics, Clinical Sciences +16

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Justin Lamb, Emily Crawford, D. D. Peck et al. · Science · 2006 · 5.5K citations

Life Sciences, Bioinformatics, Molecular Biology +16

DrugBank: a comprehensive resource for in silico drug discovery and exploration

David S. Wishart · Nucleic Acids Research · 2005 · 4K citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17