Delivery of Intact Transcription Factor by Using Self‐Assembled Supramolecular Nanoparticles

Yang Liu, Hao Wang, Ken‐ichiro Kamei, Ming Yan, Kuan‐Ju Chen, Qinghua Yuan, Linqi Shi, Yunfeng Lu, Hsian‐Rong Tseng

Angewandte Chemie International Edition · 2011 · 73 citations · 40 references

Concepts

Abstract

Special delivery: A supramolecular nanoparticle provides a facile and modular protein delivery system (see picture, TAT enables cell membrane penetration, RGD targeting, and PEG passivation) for highly efficient transduction of intact (unmodified) transcription factors (TF). Such a TF delivery approach provides a powerful method for manipulating cellular behavior. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

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