Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

Dohoon Kim, Chun‐Hyung Kim, Jung-Il Moon, +8

Cell stem cell

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellDevelopmental BiologyMedicine +11

A Quantitative-Trait Analysis of Human Plasma–Dopamine β-Hydroxylase Activity: Evidence for a Major Functional Polymorphism at the DBH Locus

Cyrus P. Zabetian, George Anderson, Sarah G. Buxbaum, +8

The American Journal of Human Genetics

Quantitative-trait AnalysisGeneticsHuman PolymorphismNeurogeneticsMajor Functional Polymorphism +5

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

Yong‐Hee Rhee, Ji‐Yun Ko, Mi‐Yoon Chang, +14

Journal of Clinical Investigation

Mda NeuronsFunctional Dopamine NeuronsRat ModelStem CellsCell Transplantation +16

Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell‐specific manner

Kwang‐Soo Kim, Chun‐Hyung Kim, Dong‐Youn Hwang, +6

Journal of Neurochemistry

Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease

Chun‐Hyung Kim, Baek‐Soo Han, Jisook Moon, +17

Proceedings of the National Academy of Sciences

A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder

Chun‐Hyung Kim, Maureen K. Hahn, Yoo‐Sook Joung, +10

Proceedings of the National Academy of Sciences

GeneticsNeurotransmitterHuman PolymorphismSocial SciencesAdhd +22

<i>Paired</i>‐Like Homeodomain Proteins, Phox2a and Phox2b, Are Responsible for Noradrenergic Cell‐Specific Transcription of the Dopamine β‐Hydroxylase Gene

Chunying Yang, Hee‐Sun Kim, Hyemyung Seo, +3

Journal of Neurochemistry

A Previously Undescribed Intron and Extensive 5′ Upstream Sequence, but Not Phox2a-mediated Transactivation, Are Necessary for High Level Cell Type-specific Expression of the Human Norepinephrine Transporter Gene

Chun‐Hyung Kim, Heesun Kim, Joseph F. Cubells, +1

Journal of Biological Chemistry

Mutations in the dopamine β‐hydroxylase gene are associated with human norepinephrine deficiency

Chun‐Hyung Kim, Cyrus P. Zabetian, Joseph F. Cubells, +5

American Journal of Medical Genetics

PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function

S. S. Rajan, Yongwoo Jang, Chun‐Hyung Kim, +22

Nature Chemical Biology

Transcriptional RegulationSignal TransductionG Protein-coupled ReceptorNatural SciencesPga1 Bind +9