Analysis of Nuclear Migration in Aspergillus nidulans

Abstract

Nuclear migration is a prominent feature of three different fundamental biological processes: separation of daughter nuclei during mitosis, congress of parental nuclei during fertilization (karyogamy), and active nuclear positioning in the interphase cell. The first two have been studied in considerable morphological, molecular, and biochemical detail, and in many different biological systems. Interphase nuclear migration has also been described morphologically in a vast number of organisms, including vertebrates, plants, algae, and fungi, but until recently, little was known about the molecular biology or biochemistry of interphase nuclear migration except that microtubules (MTs) and, in some cases, actin were involved.