Pharmacokinetic Analysis of Single- or Multiple-Dose Plasma Drug Concentration Data with a Microcomputer Using Multi-Fraction Absorption Models

A Simplex Method for Function Minimization

J. A. Nelder, R. Mead · The Computer Journal · 1965 · 28.9K citations

Natural Sciences, Computer Science, Mathematics +8

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations

Kiyoshi Yamaoka, Terumichi Nakagawa, Toyozo Uno · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 2.1K citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +11

Estimation of population characteristics of pharmacokinetic parameters from routine clinical data

Lewis B. Sheiner, Barr Rosenberg, Vinay V. Marathe · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 687 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +16

Bioavailability of cimetidine in man

Sidney S. Walkenstein, Jeffrey W. Dubb, Warren C. Randolph et al. · Gastroenterology · 1978 · 165 citations

Medicine, Pharmacokinetics, Pharmacology +4