Concepedia

Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation

Yan Xiong, Xiaopeng Jing, Xinwen Zhou, Xiulian Wang, Yang Yang, Xuying Sun, Mei Qiu, Fuyuan Cao, Youming Lu, Rong Liu,

Neurobiology of Aging · 2012 · 126 citations · 53 references

DOI

Concepts

References

53

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

, , +15

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Inge Grundke‐Iqbal, Khalid Iqbal, M Quinlan et al. · Journal of Biological Chemistry · 1986 · 1.8K citations · Full text

, , +14

Rapid induction of Alzheimer A beta amyloid formation by zinc

Ashley I. Bush, Warren H. Pettingell, Gerd Multhaup et al. · Science · 1994 · 1.5K citations

, , +17

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A. Cherny, Craig Atwood, Michel Xilinas et al. · Neuron · 2001 · 1.5K citations · Full text

, , +13

A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

Virginia M.‐Y. Lee, Brian J. Balin, László Ötvös et al. · Science · 1991 · 1.4K citations

, , +17