Concepedia

Synthesis of new camptothecin analogs with improved antitumor activities

Satoshi Niizuma, Masao Tsukazaki, Hitomi Suda, Takeshi Murata, Jun Ohwada, Sawako Ozawa, Hiroshi Fukuda, Chikako Murasaki, Masami Kohchi, Kenji Morikami,

Bioorganic & Medicinal Chemistry Letters · 2009 · 16 citations · 8 references

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8

Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

Matthew R. Redinbo, Lance Stewart, Peter Kühn et al. · Science · 1998 · 878 citations

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The mechanism of topoisomerase I poisoning by a camptothecin analog

Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

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Breast Cancer Resistance Protein Directly Confers SN-38 Resistance of Lung Cancer Cells

Shigeru Kawabata, Mikio Oka, Ken Shiozawa et al. · Biochemical and Biophysical Research Communications · 2001 · 239 citations

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Towards new anticancer drugs: a decade of advances in synthesis of camptothecins and related alkaloids

Wu Du · Tetrahedron · 2003 · 211 citations

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A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors <i>in vitro</i> and <i>in vivo</i>

Ikuo Mitsui, Eiji Kumazawa, Yasuhide Hirota et al. · Japanese Journal of Cancer Research · 1995 · 163 citations · Full text

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