Concepedia

Clinical Significance of <i>BRAF</i> Mutation in Thyroid Papillary Cancer

Ignacio Javier Fernandez, Ottavio Piccin, Silvia Sciascia, Ottavio Cavicchi, Andrea Repaci, Valentina Vicennati, Michelangelo Fiorentino

Otolaryngology · 2013 · 45 citations · 16 references

DOI

Abstract

Our results indicate that BRAF mutation identifies a subset of PTC with increased risk of recurrence. The presence of BRAF mutation might be a valuable diagnostic and prognostic marker of the disease. To confirm the diagnostic usefulness of this marker, further studies should be carried out.

References

16

BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

Marina N. Nikiforova, Edna Teruko Kimura, Manoj Gandhi et al. · The Journal of Clinical Endocrinology & Metabolism · 2003 · 1.1K citations · Full text

BRAFV600E Mutation and Outcome of Patients with Papillary Thyroid Carcinoma: A 15-Year Median Follow-Up Study

Rossella Elisei, Clara Ugolini, David Viola et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 525 citations

The Prevalence and Prognostic Value of BRAF Mutation in Thyroid Cancer

Electron Kebebew, Julie Weng, Jürgen Bauer et al. · Annals of Surgery · 2007 · 481 citations · Full text

Correlation between B-RAFV600E mutation and clinico–pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature

Laura Fugazzola, Efisio Puxeddu, Nicola Avenia et al. · Endocrine Related Cancer · 2006 · 235 citations · Full text

Immunohistochemical Detection of the BRAF V600E-mutated Protein in Papillary Thyroid Carcinoma

Oskar Koperek, Christoph Kornauth, David Capper et al. · The American Journal of Surgical Pathology · 2012 · 173 citations

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