Concepedia

Radiosensitization of metformin in pancreatic cancer cells via abrogating the G2 checkpoint and inhibiting DNA damage repair

Wang Zheng, Songtao Lai, Ningyi Ma, Yun Deng, Yong Liu, Dongping Wei, Jian-Dong Zhao, Guo-Liang Jiang

Cancer Letters · 2015 · 48 citations · 36 references

Concepts

MedicineOncologyPharmacologyDna RepairMolecular OncologyRadiobiologyCancer Cell SignalingDna Damage SignalingDna Repair In CarcinogenesisMalignant NeoplasmsPancreatic CancerSignal Transduction In CancerCancer Cell RadiosensitivityCellular RadiosensitivityDna Damage Repair PathwaysG2 Checkpoint ArrestG2/m Checkpoint ControlTherapeutic RadiosensitizationTumor Radiosensitivity

References

36

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +9

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

G2 checkpoint abrogators as anticancer drugs

Takumi Kawabe · Molecular Cancer Therapeutics · 2004 · 383 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells

Bin Bao, Zhiwei Wang, Shadan Ali et al. · Cancer Prevention Research · 2011 · 335 citations · Full text

Medicine, Oncology, Pharmacology +17

Genetic profile of 22 pancreatic carcinoma cell lines

Patrick S. Moore, Bence Sipos, Simonetta Orlandini et al. · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 2001 · 323 citations

Medicine, Genetics, Oncology +6