Concepedia

Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase

Shaun R. Selness, Terri L. Boehm, John K. Walker, Balekudru Devadas, Richard C. Durley, Ravi G. Kurumbail, H.-S. Shieh, Xing Li, Michael Hepperle, Paul V. Rucker,

Bioorganic & Medicinal Chemistry Letters · 2011 · 17 citations · 8 references

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8

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

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Efficacy and safety of retreatment with anti–tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease

Paul Rutgeerts, Geert D’Haens, Stephan R. Targan et al. · Gastroenterology · 1999 · 1.1K citations · Full text

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Quantitative analysis of cytokine gene expression in rheumatoid arthritis.

Gary S. Firestein, Richard A. Maki · The Journal of Immunology · 1990 · 601 citations · Full text

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Systemic anti-tumor necrosis factor α therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor α synthesis

Ann‐Kristin Ulfgren, Marianne Engström, Lars Klareskog et al. · Arthritis & Rheumatism · 2000 · 159 citations

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Potential of p38 inhibitors in the treatment of rheumatoid arthritis.

M. Foster, F. HALLEY, JE Souness · PubMed · 2000 · 71 citations

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