Heterocyclic system containing bridgehead nitrogen atom: synthesis and pharmacological activities of some substituted 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles

Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine · 1962 · 5.7K citations

Medicine, Pharmacology, Clinical Pharmacology +7

Improved syntheses of 5‐substituted‐4‐amino‐3‐mercapto‐(4<i>H</i>)‐1,2,4‐triazoles

Jack R. Reid, Ned D. Heindel · Journal of Heterocyclic Chemistry · 1976 · 211 citations

Pharmacy, Chemistry, Medicinal Chemistry +6

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities

Diane H. Boschelli, David T. Connor, Dirk A. Bornemeier et al. · Journal of Medicinal Chemistry · 1993 · 202 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

Paul C. Unangst, G. P. SHRUM, D. T. CONNOR et al. · Journal of Medicinal Chemistry · 1992 · 198 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

A convenient and novel synthesis of 1,2,4-triazolo(3,4-b)(1,3,4)thiadiazoles as potential pesticides.

B. CHATURVEDI, Nirupama Tiwari, NIZAMUDDIN · Agricultural and Biological Chemistry · 1988 · 19 citations · Full text

Natural Sciences, Chemistry, Drug Discovery +12