Concepedia

The Metabotropic Glutamate Receptor Subtype 5 Antagonist Fenobam Is Analgesic and Has Improved in Vivo Selectivity Compared with the Prototypical Antagonist 2-Methyl-6-(phenylethynyl)-pyridine

Michael C. Montana, Laura F. Cavallone, Kristi K. Stubbert, Andrei D. Stefanescu, Evan D. Kharasch, Robert W. Gereau

Journal of Pharmacology and Experimental Therapeutics · 2009 · 79 citations · 21 references

Open access

References

21

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Kenneth Hargreaves, Ronald Dubner, Frederick J. Brown et al. · Pain · 1988 · 5.2K citations

Medicine, Pharmacology, Behavioral Pharmacology +16

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception

Jeffrey S. Mogil, Sonya G. Wilson, Karine Bon et al. · Pain · 1999 · 658 citations

Life Sciences, Genetics, Neuroscience +17

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

Youming Lu, Zhengping Jia, Christopher Janus et al. · Journal of Neuroscience · 1997 · 630 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP

Qijiang Yan, Mustapha Rammal, Michael R. Tranfaglia et al. · Neuropharmacology · 2005 · 525 citations

Life Sciences, Neurobiology, Neuroscience +5