Study of two markers of apoptosis and meiotic segregation in ejaculated sperm of chromosomal translocation carrier patients

Abstract

Our data show a predominant proportion of balanced gametes in sperm of chromosomal translocation carrier patients. Moreover, PS externalization and DNA fragmentation rates are significantly higher in ejaculated sperm of these patients than in donor sperm. These tests could be used to predict the outcome of ICSI for these patients.