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Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

Aditi Bhattacharya, Hanoch Kaphzan, Amanda Alvarez-Dieppa, Jaclyn P. Murphy, Philippe Pierre, Eric Klann

Neuron · 2012 · 312 citations · 53 references

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53

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Annemieke J.M.H. Verkerk, Maura Pieretti, James S. Sutcliffe et al. · Cell · 1991 · 3.5K citations

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FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Jennifer C. Darnell, Sarah J. Van Driesche, Chaolin Zhang et al. · Cell · 2011 · 2.1K citations · Full text

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SUnSET, a nonradioactive method to monitor protein synthesis

Enrico Schmidt, Giovanna Clavarino, Maurizio Ceppi et al. · Nature Methods · 2009 · 1.8K citations

, , +7

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Kimberly M. Huber, Sean Gallagher, Stephen T. Warren et al. · Proceedings of the National Academy of Sciences · 2002 · 1.3K citations

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mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events

Marina K. Holz, Bryan A. Ballif, Steven P. Gygi et al. · Cell · 2005 · 1.2K citations · Full text

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