Concepedia

Sensitization to cross‐reactive carbohydrate determinants and the ubiquitous protein profilin: mimickers of allergy

Didier G. Ebo, Margo M. Hagendorens, C.H. Bridts, Luc S. De Clerck, W. J. Stevens

Clinical & Experimental Allergy · 2004 · 169 citations · 44 references

DOI

Abstract

Patients monoallergic to NRL or birch pollen showed no sensitization to bromelain-type CCD or profilin. Sensitization to profilin and/or bromelain-type CCD, caused by pollen (timothy grass, mugwort) or hymenoptera venom allergens, can elicit false-positive IgE antibodies against NRL and apple.

References

44

The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene.

Heimo Breiteneder, K. Pettenburger, A. Bito et al. · The EMBO Journal · 1989 · 678 citations · Full text

, , +6

Profilins constitute a novel family of functional plant pan-allergens.

Rudolf Valenta, Michael Duchêne, C. Ebner et al. · The Journal of Experimental Medicine · 1992 · 632 citations · Full text

, , +14

Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and Hymenoptera venom

Rob C. Aalberse, V. Koshte, John D. Clemens · Journal of Allergy and Clinical Immunology · 1981 · 414 citations

, , +9

Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)

C. Ebner, Reinhold Hirschwehr, Leonhardt Bauer et al. · Journal of Allergy and Clinical Immunology · 1995 · 407 citations

, , +10

β(1,2)-Xylose and α(1,3)-Fucose Residues Have a Strong Contribution in IgE Binding to Plant Glycoallergens

Ronald van Ree, Marion Cabanes‐Macheteau, Jaap H. Akkerdaas et al. · Journal of Biological Chemistry · 2000 · 384 citations · Full text