American Journal of Diseases of Children · 1943 · 113 citations · 8 references
DentistryDental Public HealthToxicologyEnamel BiologyEnvironmental ToxicologyPediatric Dental CariesCaries EtiologyCaries PathogenesisDental CariesEnamel CariesFluoride Effects On EnamelFluoride UseFluoride Effects On Caries ProgressionFluoride In Drinking WaterFluoride IngestionFluoride Use In ChildrenFluorine Chemistry
With few exceptions the biochemistry of fluorine emphasizes its toxic features. The production of endemic dental fluorosis (mottled enamel) in human beings by fluorine in drinking water<sup>1</sup>is an outstanding example of the toxic effect of an excessive intake of the element. The recent discovery of the inhibitory effect of trace quantities of fluorine in drinking water on dental caries in children aged 12 to 14 years<sup>2</sup>and in young adults<sup>3</sup>marks the first indication that fluorine may have a beneficial role in animal physiology. This inhibitory effect of fluorine on dental caries is shown by data in table 1 and in the chart, taken from a recent report by Dean, Arnold and Elvove.<sup>2b</sup>The figures in table 2 are from a report by Deatherage<sup>3</sup>based on results of dental examinations of selectees of the current Selective Service law. The effect of fluorine present in
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Hartley Dean, Francis A. Arnold, Elias Elvove · Public Health Reports (1896-1970) · 1942 · 424 citations
Hartley Dean, Philip Jay, Francis A. Arnold et al. · Public Health Reports (1896-1970) · 1941 · 199 citations
Dental Science and Dental Art.
Annals of Internal Medicine · 1940 · 51 citations