Concepedia

The Use of Non-Uniform Deuterium Labelling ['NMR-Window'] To Study the NMR Structure of a 21mer RNA Hairpin

András Földesi, Shun-ichi Yamakage, Frida Nilsson, T. V. Maltseva, Jyoti Chattopadhyaya

Nucleic Acids Research · 1996 · 40 citations · 26 references

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Concepts

Abstract

The first synthesis of a non-uniformly deuterium labelled 21mer RNA is reported using our 'NMR-window' concept, showing its unique application in the unambiguous NMR assignment of the non-exchangeable aromatic and sugar protons.

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