Proteolysis of human bone collagen by cathepsin K: characterization of the cleavage sites generating the cross-linked N-telopeptide neoepitope

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

Biology, Natural Sciences, Active Site +2

Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency

Bruce D. Gelb, Guo‐Ping Shi, Harold A. Chapman et al. · Science · 1996 · 1K citations

Sclerostin, Cysteine Protease Gene, Pathology +19

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

Paul Säftig, Ernst B. Hunziker, Olaf Wehmeyer et al. · Proceedings of the National Academy of Sciences · 1998 · 904 citations · Full text

Sclerostin, Health Sciences, Medicine +15

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts

Fred H. Drake, Robert A. Dodds, Ian E. James et al. · Journal of Biological Chemistry · 1996 · 711 citations · Full text

Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment.

Patrick Garnero, W J Shih, Évelyne Gineyts et al. · The Journal of Clinical Endocrinology & Metabolism · 1994 · 682 citations · Full text

Bone Disease, Bone Health, Bone Markers +13