Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma. - Concepedia

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Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.

121

Citations

37

References

2003

Year

Carmen Pingoud-Meier, Doris Lang, Anna J. Janss, Lucy B. Rorke, Peter C. Phillips∥, Tarek Shalaby, Michael A. Grotzer

Abstract

Loss of initiator caspase-8 is associated with an unfavorable survival outcome. Restoration of caspase-8 (e.g., by treatment with IFN-gamma) might, therefore, represent a novel experimental therapy in childhood MB.

References

	Year	Citations
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples Richard Peto, M. C. Pike, P. Armitage, British Journal of Cancer Retrospective Cohort StudyHealth SciencesHealth PolicyClinical Trial ManagementClinical Trial Analysis	1977	8.4K
Identification and characterization of a new member of the TNF family that induces apoptosis Steven R. Wiley, Ken Schooley, Pamela J. Smolak, Immunity InflammationCytokineSignaling PathwayMedicineReceptor Tyrosine Kinase	1995	2.9K
Prediction of central nervous system embryonal tumour outcome based on gene expression Scott L. Pomeroy, Pablo Tamayo, Michelle Gaasenbeek, Nature Neuro-oncologyDevelopmental BiologyEngineeringGliomaTumor Heterogeneity	2002	2.4K
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design Richard Peto, Malcolm C. Pike, P. Armitage, British Journal of Cancer Retrospective Cohort StudyHealth SciencesClinical Trial AnalysisClinical Trial ManagementClinical Endpoint	1976	2.3K
Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells Claudia Friesen, Ingrid Herr, Peter H. Krammer, Nature Medicine Hematological MalignancyReceptor/ligand SystemMedicineApoptosisImmunology	1996	994
Postoperative Chemotherapy and Delayed Radiation in Children Less Than Three Years of Age with Malignant Brain Tumors Patricia K. Duffner, Marc E. Horowitz, Jeffrey P. Krischer, New England Journal of Medicine	1993	843
An Operative Staging System and a Megavoltage Radiotherapeutic Technic for Cerebellar Medulloblastomas Chu H. Chang, Edgar M. Housepian, Charles Herbert Radiology	1969	775
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer Robert Pitti, Scot A. Marsters, David A. Lawrence, Nature Genomic AmplificationEngineeringDecoy ReceptorMedicineBiomarker Target	1998	770
Metastasis Stage, Adjuvant Treatment, and Residual Tumor Are Prognostic Factors for Medulloblastoma in Children: Conclusions From the Children's Cancer Group 921 Randomized Phase III Study Paul M. Zeltzer, James M. Boyett, Jonathan L. Finlay, Journal of Clinical Oncology	1999	748
TRAIL receptor-2 signals apoptosis through FADD and caspase-8 Jean-Luc Bodmer, Nils Holler, Séverine Reynard, Nature Cell Biology Trail Receptor-2 SignalsSignal TransductionSignaling PathwayApoptosisAutophagy	2000	646

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