Concepedia

Extended structure–activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties

Steffen Bugge, Audun Formo Buene, Nathalie Jurisch‐Yaksi, Ingri Ullestad Moen, Ellen Martine Skjønsfjell, Eirik Sundby, Bård Helge Hoff

European Journal of Medicinal Chemistry · 2015 · 47 citations · 38 references

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38

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

, , +16

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

Nicholas A. Meanwell · Journal of Medicinal Chemistry · 2011 · 2.8K citations · Full text

, , +11

Novel Procedure for Modeling Ligand/Receptor Induced Fit Effects

Woody Sherman, Tyler Day, Matthew P. Jacobson et al. · Journal of Medicinal Chemistry · 2005 · 2K citations

, , +16

Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker

Flavio Solca, G. Dahl, Andreas Zoephel et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 867 citations

, , +16

Lipophilicity in drug discovery

Michael J. Waring · Expert Opinion on Drug Discovery · 2010 · 844 citations

, , +13