Investigation of MicroRNA Expression in Human Serum During the Aging Process

Abstract

The measurement of miRNAs in serum provides a novel, noninvasive approach for the identification of the aging process. Our bioinformatic analyses could form a useful knowledge base for the potential future development of novel therapeutic treatments.

References

Page 1

	Year	Citations
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Rosalind C. Lee, Rhonda Feinbaum, Victor Ambros Cell	1993	12.7K
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Hadi Valadi, Karin M. Ekström, Apostolos Bossios, Nature Cell Biology Novel MechanismSystems BiologyNatural SciencesExosome-mediated TransferExtracellular Microvesicles	2007	12.6K
A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing Pablo Landgraf, Mirabela Rusu, Robert P. Sheridan, Cell Systems BiologyFunctional GenomicsEngineeringGeneticsComputational Biology	2007	3.6K
Identification of Tissue-Specific MicroRNAs from Mouse Mariana Lagos‐Quintana, Reinhard Rauhut, Abdullah Yalçın, Current Biology Functional GenomicsMicrorna DetectionSmall RnaGene ExpressionMedicine	2002	3.3K
A pancreatic islet-specific microRNA regulates insulin secretion Matthew N. Poy, Lena Eliasson, Jan Krützfeldt, Nature DiabetesMicrorna DetectionGene ExpressionMedicineCell Biology	2004	2.1K
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells Marı́a Mittelbrunn, Cristina Gutiérrez‐Vázquez, Carolina Villarroya‐Beltri, Nature Communications	2011	1.7K
Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration Yujing Zhang, Danqing Liu, Xi Chen, Molecular Cell InflammationAngiogenesisEndothelial Cell MigrationVascular BiologyMicrorna Detection	2010	1.2K
A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Xiaojun Liu, Yunhui Cheng, Shuo Zhang, Circulation Research	2009	548
miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging Matthias Hackl, Stefan M. Brunner, Klaus Fortschegger, Aging Cell AgingAnti-agingEndothelial CellsGeneticsSingle Mirna	2010	353
microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age Nicole Noren Hooten, Kotb Abdelmohsen, Myriam Gorospe, PLoS ONE Developmental BiologyGeneticsCancer PathogenesisRna BiologyPathology	2010	349

Page 1