Concepedia

Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling of the Respiratory-Depressant Effect of Buprenorphine and Fentanyl in Rats

Ashraf Yassen, Jingmin Kan, Erik Olofsen, Ernst Suidgeest, Albert Dahan, Meindert Danhof

Journal of Pharmacology and Experimental Therapeutics · 2006 · 43 citations · 32 references

DOI

References

32

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

Operational models of pharmacological agonism

J.W. Black, P. Leff · Proceedings of the Royal Society of London. Series B, Biological sciences · 1983 · 1.1K citations

Trends in Medical Use and Abuse of Opioid Analgesics

David E. Joranson · JAMA · 2000 · 496 citations

Simultaneous vs. Sequential Analysis for Population PK/PD Data I: Best-Case Performance

Liping Zhang, Stuart L. Beal, Lewis B. Sheiner · Journal of Pharmacokinetics and Pharmacodynamics · 2003 · 359 citations

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Comparison of Pharmacological Activities of Buprenorphine and Norbuprenorphine: Norbuprenorphine Is a Potent Opioid Agonist

George B. Kehner, A. Cowan, Lee‐Yuan Liu‐Chen · Journal of Pharmacology and Experimental Therapeutics · 2001 · 340 citations