Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.2K citations

Crac Channel Function, Immunogenetics, Molecular Immunology +10

Signaling to the Nucleus by an L-type Calcium Channel-Calmodulin Complex Through the MAP Kinase Pathway

Ricardo E. Dolmetsch, Urvi Pajvani, Katherine Fife et al. · Science · 2001 · 898 citations

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen et al. · Proceedings of the National Academy of Sciences · 2006 · 804 citations · Full text

Cdk1 Inhibition, Immunology, Human Cdk1 +17

STIM2 Is a Feedback Regulator that Stabilizes Basal Cytosolic and Endoplasmic Reticulum Ca2+ Levels

Onn Brandman, Jen Liou, Wei Sun Park et al. · Cell · 2007 · 682 citations · Full text

Feedback Regulator, Molecular Physiology, Signal Transduction +11

STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

Guo N. Huang, Weizhong Zeng, Joo Young Kim et al. · Nature Cell Biology · 2006 · 629 citations · Full text

Molecular Physiology, Signal Transduction, G Protein-coupled Receptor +6