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Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

DOIFull Paper Access

193

Citations

38

References

2009

Year

Yi Huang, Tracy Murray Stewart, Yu Wu, Stephen B. Baylin, Laurence J. Marton, Brandy Perkins, Richard J. Jones, Patrick M. Woster, Robert A. Casero
Clinical Cancer Research

Abstract

The use of LSD1-inhibiting oligoamine analogues in combination with DNA methyltransferase inhibitors represents a highly promising and novel approach for epigenetic therapy of cancer.

References

YearCitations

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