Protein-resistant, reductively dissociable polyplexes for in vivo systemic delivery and tumor-targeting of siRNA

Gene therapy - promises, problems and prospects

Inder M. Verma, Nikunj V. Somia · Nature · 1997 · 1.7K citations · Full text

Gene Therapies, Novel Therapy, Genetic Engineering +5

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

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Nanoparticles, Nanomedicine, Drug Targeting +7

Dynamic PolyConjugates for targeted <i>in vivo</i> delivery of siRNA to hepatocytes

David B. Rozema, David L. Lewis, Darren H. Wakefield et al. · Proceedings of the National Academy of Sciences · 2007 · 679 citations · Full text

Engineering, Molecular Biology, Gene Delivery +17

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

Ya‐Lin Chiu, Akbar Ali, Chia‐Ying Chu et al. · Chemistry & Biology · 2004 · 377 citations · Full text

Medicine, Cellular Uptake, Sirna Localization +7

Design of a genome-wide siRNA library using an artificial neural network

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Functional Genomics, Genome-wide Sirna Library, Bioinformatics Database +12