Epilepsia · 2009 · 53 citations · 33 references
The pattern of SV2A immunoreactivity with reduced neuropil expression and altered cellular and subcellular distribution suggests a possible contribution of SV2A to the epileptogenicity of these malformations of cortical development. Knowledge of the expression pattern of SV2A in epilepsy-associated pathologies may be valuable for the evaluation of the effectiveness of AEDs targeting this protein.
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The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
Berkley A. Lynch, Nathalie Lambeng, Karl Nocka et al. · Proceedings of the National Academy of Sciences · 2004 · 1.6K citations · Full text
New Antiepileptic Drug, Molecular Neuroscience, Antiepileptic Drug Levetiracetam +15
A new collection method for the evaluation of nasal mucus proteins
L. Ruocco, Fattori, Romanelli et al. · Clinical & Experimental Allergy · 1998 · 1.3K citations
Differential expression of synaptic vesicle protein 2 (SV2) isoforms
SM Bajjalieh, GD Frantz, JM Weimann et al. · Journal of Neuroscience · 1994 · 457 citations · Full text
Protein Secretion, Synaptic Transmission, Molecular Biology +21