Concepedia

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

Chunhong Yan, Dan Lü, Tsonwin Hai, Douglas D. Boyd

The EMBO Journal · 2005 · 217 citations · 38 references

DOIFull text

Open access

Concepts

References

38

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

, , +10

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

, , +10

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

Roberto Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano · Nature · 1995 · 1.4K citations

, , +12

Diversity of gene expression in adenocarcinoma of the lung

Mitchell Garber, Olga G. Troyanskaya, Karsten Schluens et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text

, , +17