Nuclear pockets associated with the nucleolus in normal and neoplastic cells.

Abstract

Cytoplasmic projections into the nucleus forming nuclear pockets have been observed in Ehrlich ascites tumor cells, chick embryo lens, human amelanotic malignant melanoma, human corneal epithelium from Fuchs' dystrophy, and raccoon spinal neurons. A significant proportion of these pockets were related structurally to the nucleolus. These configurations are believed to be related to enhancement of nucleolocytoplasmic interaction.