BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Arnold van Loevezijn, Jeany M Lakhai, Martin van der Valk et al. · PubMed · 2002 · 687 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan

Johan W. Jonker · JNCI Journal of the National Cancer Institute · 2000 · 639 citations · Full text

Medicine, Oncology, Pharmacology +17

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk

Johan W. Jonker, Gracia Merino, Sandra Musters et al. · Nature Medicine · 2005 · 420 citations

Medicine, Oncology, Pharmacology +13

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Herman Burger, Hans van Tol, Antonius W.M. Boersma et al. · Blood · 2004 · 415 citations · Full text

Medicine, Molecular Biology, Oncology +11

Human Breast Cancer Resistance Protein: Interactions with Steroid Drugs, Hormones, the Dietary Carcinogen 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and Transport of Cimetidine

Petr Pávek, Gracia Merino, Els Wagenaar et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 278 citations

Medicine, Oncology, Pharmacology +15