A Nuclear Factor-κB Inhibitor Pyrrolidine Dithiocarbamate Ameliorates Pulmonary Hypertension in Rats

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

Ralf Schreck, Beate Meier, Daniela N. Männel et al. · The Journal of Experimental Medicine · 1992 · 1.5K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

Amer A. Beg, Timothy S. Finco, Pascale V. Nantermet et al. · Molecular and Cellular Biology · 1993 · 1K citations · Full text

Life Sciences, Cell Biology, Immunology +11

Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension.

Rubin M. Tuder, Bertron Μ. Groves, David B. Badesch et al. · PubMed · 1994 · 803 citations

Medicine, Clinical Sciences, Pathology +10

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

Korbinian Brand, Sharon Page, Gerhard Rogler et al. · Journal of Clinical Investigation · 1996 · 801 citations · Full text

Life Sciences, Molecular Biology, Pathobiology +15

Increased Interleukin-1 and Interleukin-6 Serum Concentrations in Severe Primary Pulmonary Hypertension

Marc Humbert, Gianpaola Monti, F Brénot et al. · American Journal of Respiratory and Critical Care Medicine · 1995 · 786 citations

Medicine, Immunology, Pathobiology +16