Hirofumi Sawada

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

Edda Spiekerkoetter, Xuefei Tian, Jie Cai et al. · Journal of Clinical Investigation · 2013 · 432 citations · Full text

Inflammation, Pulmonary Arterial Hypertension, Molecular Physiology +15

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

Tero‐Pekka Alastalo, Molong Li, Vinicio de Jesús Pérez et al. · Journal of Clinical Investigation · 2011 · 251 citations · Full text

Lung Inflammation, Pparγ/β-catenin–mediated Regulation, Immunology +21

Autophagic Protein LC3B Confers Resistance against Hypoxia-induced Pulmonary Hypertension

Seon‐Jin Lee, Akaya Smith, Lanping Guo et al. · American Journal of Respiratory and Critical Care Medicine · 2010 · 211 citations · Full text

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

Christophe Guignabert, Cristina M. Alvira, Tero‐Pekka Alastalo et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2009 · 155 citations · Full text

Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension

Hirofumi Sawada, Toshie Saito, Nils Nickel et al. · The Journal of Experimental Medicine · 2014 · 145 citations · Full text