Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug–associated torsades de pointes

Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo

Debra S. Echt, Philip R. Liebson, L. Brent Mitchell et al. · New England Journal of Medicine · 1991 · 3.3K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

Medicine, Genetics, Molecular Genetics +13

The Spectrum of Symptoms and QT Intervals in Carriers of the Gene for the Long-QT Syndrome

G. Michael Vincent, Katherine W. Timothy, Mark Leppert et al. · New England Journal of Medicine · 1992 · 624 citations

Life Sciences, Cardiology, Genetics +13

Allelic Variants in Long-QT Disease Genes in Patients With Drug-Associated Torsades de Pointes

Ping Yang, Hideaki Kanki, Benoît Drolet et al. · Circulation · 2002 · 552 citations

Life Sciences, Genetics, Molecular Genetics +17

Variant of SCN5A Sodium Channel Implicated in Risk of Cardiac Arrhythmia

Igor Splawski, Katherine W. Timothy, Michihiro Tateyama et al. · Science · 2002 · 523 citations

Medicine, Genetics, Molecular Genetics +17