Mutations of the Cardiac Ryanodine Receptor (RyR2) Gene in Familial Polymorphic Ventricular Tachycardia

Päivi J. Laitinen, Kevin M. Brown, Kirsi Piippo, +10

Circulation

Arrhythmic disorder mapped to chromosome 1q42–q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts

Heikki Swan, Kirsi Piippo, Matti Viitasalo, +7

Journal of the American College of Cardiology

Normal HeartsCardiac MuscleCardiomyopathyStructural Heart DiseaseMedicine +7

Sudden Death in Familial Polymorphic Ventricular Tachycardia Associated With Calcium Release Channel (Ryanodine Receptor) Leak

Stephan E. Lehnart, Xander H.T. Wehrens, Päivi J. Laitinen, +7

Circulation

High Efficacy of β-Blockers in Long-QT Syndrome Type 1

G. Michael Vincent, Peter J. Schwartz, Isabelle Denjoy, +10

Circulation

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

Anna Lahti, Ville Kujala, Hugh Chapman, +10

Disease Models & Mechanisms

Cardiac MuscleHeart FailureImmunodeficienciesImmunologyCell Culture +18

Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects

Heikki Swan, Matti Viitasalo, Kirsi Piippo, +3

Journal of the American College of Cardiology

Electrophysiological EvaluationKinesiologyHealth SciencesPhysiologyExercise Physiology +7

The Common Long-QT Syndrome Mutation KCNQ1/A341V Causes Unusually Severe Clinical Manifestations in Patients With Different Ethnic Backgrounds

Lia Crotti, Carla Spazzolini, Peter J. Schwartz, +13

Circulation

Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Reveals Early and Delayed Afterdepolarizations

Kirsi Kujala, Jere Paavola, Anna Lahti, +10

PLoS ONE

Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest

Christian van der Werf, Krystien V.V. Lieve, J. Martijn Bos, +34

European Heart Journal

A founder mutation of the potassium channel KCNQ1 in long QT syndrome

Kirsi Piippo, Heikki Swan, Michael Pasternack, +5

Journal of the American College of Cardiology

Founder MutationLong Qt SyndromeChannelopathiesHyperpolarization (Biology)Genetics +6