Hugh Chapman

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

Anna Lahti, Ville Kujala, Hugh Chapman et al. · Disease Models & Mechanisms · 2011 · 288 citations · Full text

Cardiac Muscle, Heart Failure, Immunodeficiencies +20

A founder mutation of the potassium channel KCNQ1 in long QT syndrome

Kirsi Piippo, Heikki Swan, Michael Pasternack et al. · Journal of the American College of Cardiology · 2001 · 131 citations

Founder Mutation, Long Qt Syndrome, Channelopathies +8

Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: Sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy

Ari Koivisto, Mika Hukkanen, Marja Saarnilehto et al. · Pharmacological Research · 2011 · 128 citations

Trpa1 Channel, Medicine, Diabetes +8

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat

Hong Wei, Ari Koivisto, Marja Saarnilehto et al. · Pain · 2011 · 93 citations

Acute Pain, Pain Medicine, Synaptic Transmission +20

Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat

Hong Wei, Hugh Chapman, Marja Saarnilehto et al. · Neuropharmacology · 2009 · 85 citations

Inflammation, Spinal Trpa1 Channels, Mechanical Hypersensitivity +6