Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2 - Concepedia

Concepedia

Publication | Open Access

Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2

DOI Full Paper Access

16

Citations

39

References

2014

Year

Meilang Xue, Kaitlin Shen, Kelly J. McKelvey, Juan Li, Yee-Ka Agnes Chan, Vicky Hatzis, Lyn March, Christopher B. Little, Michael A. Tonkin, Chris Jackson

Arthritis Research & Therapy

Abstract

Our results demonstrate that EPCR is overexpressed by RASFs and mediates the aggressive behavior of RASFs. This function of EPCR is contrary to its cytoprotective role in other settings and is likely driven by sPLA₂V.

References

	Year	Citations

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