Concepedia

KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

Antonio Montalbán, Erik Boman, Chau-Dung Chang, Susana Conde Ceide, Russell Dahl, David Dalesandro, Nancy G. J. Delaet, Eric Erb, Justin T. Ernst, Andrew R. Gibbs,

European Journal of Pharmacology · 2010 · 12 citations · 31 references

DOI

Concepts

References

31

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

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A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

Jiahuai Han, Jeffrey Lee, L. Bibbs et al. · Science · 1994 · 2.7K citations

, , +13

The stress-activated protein kinase subfamily of c-Jun kinases

John Kyriakis, Papia T. Banerjee, Eleni Nikolakaki et al. · Nature · 1994 · 2.6K citations

, , +13

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 834 citations · Full text

, , +15

Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function.

A M Badger, Jeremy N. Bradbeer, Bartholomew J. Votta et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 499 citations

, , +17