Concepedia

Crosstalk between Mast Cells and Pancreatic Cancer Cells Contributes to Pancreatic Tumor Progression

Matthew J. Strouch, Eric C. Cheon, Mohammad R. Salabat, Seth B. Krantz, Elias Gounaris, Laleh G. Melstrom, Surabhi Dangi‐Garimella, Hidayatullah G. Munshi, Khashayarsha Khazaie, David J. Bentrem

Clinical Cancer Research · 2010 · 192 citations · 22 references

DOIFull text

Open access

Abstract

Tumor-infiltrating mast cells are associated with worse prognosis in pancreatic cancer. In vitro, the interaction between mast cells and pancreatic cancer cells promotes tumor growth and invasion.

References

22

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Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2008 · 10.2K citations · Full text

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Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI

Arnold S. Kirshenbaum, Cem Akin, Yalin Wu et al. · Leukemia Research · 2003 · 501 citations

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SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

Bo Huang, Lei Zhang, Guimei Zhang et al. · Blood · 2008 · 340 citations · Full text

Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype

Hong Ouyang, Lun-jun Mou, Catherine Luk et al. · American Journal Of Pathology · 2000 · 313 citations · Full text

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Tumor vascularity and tryptase‐positive mast cells correlate with a poor prognosis in melanoma

Doménico Ribatti, Maria Grazia Ennas, Angelo Vacca et al. · European Journal of Clinical Investigation · 2003 · 257 citations