Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

Genetics, Genomic Mechanism, Gene Regulation +5

Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4

Lisa Ann Cirillo, Frank R. Lin, Isabel Cuesta et al. · Molecular Cell · 2002 · 1.2K citations · Full text

Chromatin, Transcriptional Regulation, Developmental Biology +14

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

Maryam Afkarian, John R. Šedý, Jianfei Yang et al. · Nature Immunology · 2002 · 999 citations

Inflammation, T-regulatory Cell, Immunology +9

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

Ichiro Taniuchi, Motomi Osato, Takeshi Egawa et al. · Cell · 2002 · 721 citations · Full text

Immunogenetics, Developmental Biology, Runx Proteins +10

Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

Suneet Agarwal, Anjana Rao · Immunity · 1998 · 687 citations · Full text

Chromatin, Chromatin Structure, T Cell Differentiation +12