Publication | Open Access
Water‐Soluble Monofunctional Perylene and Terrylene Dyes: Powerful Labels for Single‐Enzyme Tracking
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Citations
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References
2008
Year
Fluorescent BackgroundSingle Molecule BiophysicsBiochemistryNatural SciencesMolecular BiologyWater‐soluble Monofunctional PeryleneSingle MoleculeSingle‐enzyme TrackingTerrylene DyesChemical ProbeSingle EnzymesSingle-molecule DetectionBio-orthogonal ChemistryBiomolecular Engineering
All in one: Exceptionally photostable, highly fluorescent, water-soluble, and monofunctional perylene and terrylene dyes bearing reactive groups for covalent attachment to biomolecules have been synthesized (see picture). Single-molecule enzyme tracking revealed that single enzymes could be visualized even on a substrate with fluorescent background.
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