IEEE Transactions on Biomedical Engineering · 2013 · 29 citations · 28 references
EngineeringBioengineeringBiomedical EngineeringBiomedical ImagingDiagnostic ImagingNeural EngineeringBrain ImagingHead AnatomyNeural Signal AcquisitionAccuracyComputational Reconstruction AlgorithmsElectrical Impedance TomographyFabricationGeometric Accuracy TestingImpedance ReconstructionMold FabricationReconstruction Algorithms
Brain electrical impedance tomography (EIT) is an emerging method for monitoring brain injuries. To effectively evaluate brain EIT systems and reconstruction algorithms, we have developed a novel head phantom that features realistic anatomy and spatially varying skull resistivity. The head phantom was created with three layers, representing scalp, skull, and brain tissues. The fabrication process entailed 3-D printing of the anatomical geometry for mold creation followed by casting to ensure high geometrical precision and accuracy of the resistivity distribution. We evaluated the accuracy and stability of the phantom. Results showed that the head phantom achieved high geometric accuracy, accurate skull resistivity values, and good stability over time and in the frequency domain. Experimental impedance reconstructions performed using the head phantom and computer simulations were found to be consistent for the same perturbation object. In conclusion, this new phantom could provide a more accurate test platform for brain EIT research.
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Design and construction of a realistic digital brain phantom
D. Louis Collins, Alex Zijdenbos, Vasken Kollokian et al. · IEEE Transactions on Medical Imaging · 1998 · 1.8K citations