Myricetin: A Naturally Occurring Regulator of Metal‐Induced Amyloid‐β Aggregation and Neurotoxicity

Abstract

Berry good news for the brain: Reactivity of myricetin, a naturally occurring flavonoid (see chemical structure), was investigated in relation to metal-associated amyloid-β (Aβ) species. Myricetin was preferentially effective against metal-associated Aβ over metal-free Aβ species, and was able to modulate metal-induced Aβ aggregation and neurotoxicity in vitro and in human neuroblastoma cells. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.