Antisense Oligonucleotide Inhibition of Bcl-xL and Bid Expression in Liver Regulates Responses in a Mouse Model of Fas-Induced Fulminant Hepatitis

Lethal effect of the anti-Fas antibody in mice

Jun Ogasawara, Rie Watanabe‐Fukunaga, Masashi Adachi et al. · Nature · 1993 · 1.9K citations

Life Sciences, Immunology, Pathology +14

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

Deborah J. Veis, Christine M. Sorenson, John R. Shutter et al. · Cell · 1993 · 1.6K citations

Life Sciences, Genetics, Pathobiology +8

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

Noboru Motoyama, Fanping Wang, Kevin A. Roth et al. · Science · 1995 · 1.2K citations

Life Sciences, Developmental Biology, Neuroscience +17

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

Xiao‐Ming Yin, Kun Wang, Atan Gross et al. · Nature · 1999 · 993 citations

Life Sciences, Cell Biology, Molecular Biology +14

2′-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells

Brenda F. Baker, Sidney S. Lot, Thomas P. Condon et al. · Journal of Biological Chemistry · 1997 · 377 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15