Concepedia

Relationship between soluble markers of immune activation and bone turnover in post-menopausal women with rheumatoid arthritis

Peter Oelzner, Sybille Franke, Andreas J. Müller, Gert Hein, G Stein

Lara D. Veeken · 1999 · 67 citations · 30 references

DOI

Abstract

Our data indicate that IL-6 is a critical determinant of increased bone resorption in post-menopausal RA women with high disease activity and that serum levels of 1,25(OH)2D3 are inversely related to T-cell activation.

References

30

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Frank C. Arnett, Steven M. Edworthy, D. Blöch et al. · Arthritis & Rheumatism · 1988 · 19.8K citations

Generalised bone loss in patients with early rheumatoid arthritis

Andrew Gough · The Lancet · 1994 · 635 citations

, , +6

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

Shigeru Kotake, Kazuto Sato, Kang Jung Kim et al. · Journal of Bone and Mineral Research · 1996 · 542 citations

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors.

Nobuyuki Udagawa, N. Takahashi, Takashi Katagiri et al. · The Journal of Experimental Medicine · 1995 · 413 citations · Full text

, , +15

Bone marrow, cytokines, and bone remodeling

Stavros C. Manolagas · Biomedicine & Pharmacotherapy · 1995 · 389 citations

, , +6