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Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

Rate-limiting StepsMiniscale Dissolution TestMedicineDrug PurityPhysiologyPoorly Water-soluble DrugsDrug AbsorptionPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsDrug Analysis