Concepedia

Single Liver Lobe Repopulation with Wildtype Hepatocytes Using Regional Hepatic Irradiation Cures Jaundice in Gunn Rats

Hongchao Zhou, Xinyuan Dong, Rafi Kabarriti, Yong Chen, Yesim Avsar, Xia Wang, Jianqiang Ding, Laibin Liu, Ira J. Fox, Jayanta Roy‐Chowdhury,

PLoS ONE · 2012 · 38 citations · 22 references

DOIFull text

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Abstract

As little as 20% repopulation of 30% of the liver volume was sufficient to correct hyperbilirubinemia in Gunn rats, highlighting the potential of regiospecific HIR in hepatocyte transplantation-based therapy of inherited metabolic liver diseases.

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