Chemical Communications · 2011 · 73 citations · 34 references
Natural SciencesChemistryMedicinal ChemistryInorganic ChemistryStructural BiologyStructure-activity RelationshipsBioinorganic ChemistryCoordination ChemistryHost-guest ChemistryLigand BindingProtein-ligand BindingCarbonic Anhydrase FunctionHost - Guest CatalysisHost-guest InteractionsStructural Characterization Of Complexes
d(6)-piano-stool complexes bearing an arylsulfonamide anchor display sub-micromolar affinity towards human Carbonic Anhydrase II (hCA II). The 1.3 Å resolution X-ray crystal structure of [(η(6)-C(6)Me(6))Ru(bispy 3)Cl](+)⊂ hCA II highlights the nature of the host-guest interactions.
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The maximal affinity of ligands
Irwin D. Kuntz, K. Chen, Kim A. Sharp et al. · Proceedings of the National Academy of Sciences · 1999 · 845 citations