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The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

Viral ReplicationSignal TransductionGlucocorticoid Receptor ComplexG Protein-coupled ReceptorHuman RetrovirusImmunologyAntiviral ResponseMolecular BiologyVirologyHiv-1 VprVirus-host InteractionHivMedicineCell BiologyCell SignalingNuclear Localization