Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek, +4

Science

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick

Nature

Cancer ResearchOncologyColon Carcinoma CellsGastrointestinal OncologyMedicine +8

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin, +5

Science

Tcf Reporter GenePathologyCancer BiologyTumor BiologyConstitutive Transcriptional Activation +16

Wnt signaling and cancer

Paul Polakis

Genes & Development

Tumor BiologySignaling PathwayGene Expression ProfileOncogenic AgentMedicine +13

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

Marc van de Wetering, Elena Sancho, Cornelis L. Verweij, +15

Cell

Crypt Progenitor PhenotypeTumor BiologyMedicineCancer Cell BiologyColorectal Cancer +9

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

Vladimír Kořínek, Nick Barker, Petra Moerer, +4

Nature Genetics

InflammationDevelopmental BiologyTissue DevelopmentMucosal ImmunologySmall Intestine +7

Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.

Hiroshi Kawasaki, Dario C. Altieri, C Lu, +3

PubMed

OncologyTumor Cell ApoptosisChemoprevention StrategyGastrointestinal OncologyApoptosis Inhibition +12

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

Marc van de Wetering, Mariëtte A. Oosterwegel, Dennis Dooijes, +1

The EMBO Journal

ImmunogeneticsTranscriptional RegulationImmunologySequence-specific Hmg BoxT Cell Immunity +6

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

Colette Adida, P. Crotty, John J. McGrath, +3

PubMed

Apoptosis and APC in colorectal tumorigenesis.

Patrice J. Morin, B Vogelstein, Kenneth W. Kinzler

Proceedings of the National Academy of Sciences

ApoptosisColorectal TumorigenesisPathologyCell DeathCancer Biology +15