European Journal of Public Health · 2005 · 27 citations · 19 references
Public HealthHealth BehaviorBehavioral HealthPsychometricsSubstance Use DisordersHealth Status MeasurementNicotine DependenceSmoking CessationTobacco DependenceTobacco UseTobacco Use DisorderFollow-up Survey DesignHealth Status IndicesHealth Status InstrumentsLong-term AbstinenceNicotine Dependence MeasurementPerceived Status DifferencesSustained AbstinenceTobacco Dependence Assessment
BACKGROUND: This study evaluated change in health status as a function of change in smoking status among patients treated clinically for nicotine dependence by comparing overall perceived health status of patients who abstained from cigarettes for 1 year versus those who smoked continuously for 1 year. METHODS: Patients from the Mayo Clinic Nicotine Dependence Center completed a quality-of-life questionnaire (SF-36) following their consultation for nicotine dependence (baseline). At 1 year post-intervention, patients were mailed a follow-up survey that included the SF-36 and items assessing interval smoking history. Study patients included those who self-reported continuous smoking (n=60) and those reporting continuous smoking abstinence for the entire follow-up year (n=146). Data from SF-36 scales at 1 year were analysed using analysis of covariance with baseline scale scores serving as covariates along with baseline characteristics that differed significantly between groups. RESULTS: Compared with those who continued to smoke, patients who were continuously abstinent from smoking for the entire year had more improvement in perceived health status for the SF-36 mental composite scale (P=0.009) and for the SF-36 subscales for role limitations (P<0.001 and P=0.017 for emotional and physical role limitations, respectively), social functioning (P=0.010) and general health (P=0.013). CONCLUSIONS: Smokers treated for nicotine dependence who stop smoking for a year report more improvement in-quality-of-life compared with those who continue to smoke.
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Measures of abstinence in clinical trials: issues and recommendations
John R. Hughes, Josue Keely, Raymond Niaura et al. · Nicotine & Tobacco Research · 2003 · 1.1K citations · Full text
Gillian Hawker, Catherine A. Melfi, Jennifer J. Paul et al. · PubMed · 1995 · 276 citations